Adenylate Kinase 2 Proteins

Protein Information

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene.

Synonyms

adenylate kinase 2; adenylate kinase 2, mitochondrial; adenylate kinase 2, mitochondrial {ECO:0000255; Adenylate kinase 2, mitochondrial, N-terminally processed; adenylate kinase isoenzyme 2, mitochondrial; Adenylate monophosphate kinase; adenylate monophosphate kinase {ECO:0000255; ADK2; AK 2; AK 2 {ECO:0000255; AK2; Ak-2; ATP:AMP phosphotransferase; ATP:AMP phosphotransferase {ECO:0000255; ATP-AMP transphosphorylase 2; ATP-AMP transphosphorylase 2 {ECO:0000255; D4Ertd220e; HAMAP-Rule:MF_03168}; si:ch211-197n10.1; testis secretory sperm-binding protein Li 220n; wu:fb34f05; wu:fj80e03